Plasmonics-enhanced and optically modulated delivery of gold nanostars into brain tumor.

نویسندگان

  • Hsiangkuo Yuan
  • Christy M Wilson
  • Jun Xia
  • Sarah L Doyle
  • Shuqin Li
  • Andrew M Fales
  • Yang Liu
  • Ema Ozaki
  • Kelly Mulfaul
  • Gabi Hanna
  • Gregory M Palmer
  • Lihong V Wang
  • Gerald A Grant
  • Tuan Vo-Dinh
چکیده

Plasmonics-active gold nanostars exhibiting strong imaging contrast and efficient photothermal transduction were synthesized for a novel pulsed laser-modulated plasmonics-enhanced brain tumor microvascular permeabilization. We demonstrate a selective, optically modulated delivery of nanoprobes into the tumor parenchyma with minimal off-target distribution.

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عنوان ژورنال:
  • Nanoscale

دوره 6 8  شماره 

صفحات  -

تاریخ انتشار 2014